基本情形
赵登高，男，1982年生 ，湖南邵阳人，博士，副教授。
联系方式
地点：：：广东江门市东城村22号壹号娱乐APP药学与食物工程学院，邮编：：：529020
电话：：：0750-3299391
E-mail：：：wyuchemzdg@126.com
教育履历
2008/09--2013/06， 兰州大学，有机化学， 博士
2001/09--2005/06， 兰州大学，化学，学士
科研偏向
（1）自然活性因素的发明 、、、结构修饰与刷新。
（2）新型卵白降解剂的设计与合成。
揭晓论文
（1） Mo, H.; Liu, J.; Yin, T.; Cao, X.; Su, Z.; Zhao, D.-G.*; Ma, Y.-Y.*, Discovery of a Selective and Orally Bioavailable RET Degrader with Effectiveness in Various Mutations. J. Med. Chem. 2025, https://doi.org/10.1021/acs.jmedchem.4c01889.
（2） Zhao, D. G.*; Liu, J.; Su, Z.; Zou, W.; Zhou, Q.; Yin, T.; Jiyao, T.; Ma, Y. Y., * Discovery of novel KSP-targeting PROTACs with potent antitumor effects in vitro and in vivo. Euro. J. Med. Chem. 2025, 282, 117052.
（3） Mo, H.; Liu, J.; Su, Z.; Zhao, D. G.; Ma, Y. Y.; Zhang, K.; Wang, Q.; Fu, C.; Wang, Y.; Chen, M.; Hu, B., Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy. Euro. J. Med. Chem. 2024, 277, 116765. 2024.8
（4） Shu-Ting Li, Dan Xu, Jing Jia, Wenbo Zou, Jieying Liu, Yao Wang, Kun Zhang, Xi Zheng, Yan-Yan Ma*; Xuejian Zhang, Deng-Gao Zhao *, Structure and anti-inflammatory activity of neo-clerodane diterpenoids from Scutellaria barbata. Phytochemistry 2023, 213,113771.
（5） Mo, H.; Zhang, R.; Chen, Y.; Li, S.; Wang, Y.; Zou, W.; Lin, Q.; Zhao, D.-G. *; Du, Y. *; Zhang, K.; Ma, Y.-Y. *, Synthesis and anticancer activity of novel histone deacetylase inhibitors that inhibit autophagy and induce apoptosis. Euro. J. Med. Chem. 2022, 114705.
（6） Xuan He, Man Zhang, Shu-Ting Li, Xinyu Li, Qingrong Huang, Kun Zhang, Xi Zheng, Xue-Tao Xu, Deng- Gao Zhao*, Yan- Yan Ma*. Alteration of gut microbiota in high- fat diet- induced obese mice using carnosic acid from rosemary. Food Science & Nutrition, 2022, 00, 1– 8.
（7） Ruiqiang Zhang, Hualong Mo, Yan-Yan Ma, Deng-Gao Zhao*, Tingwen Zhang, Xue cheng Chen, Kun Zhang, Xi Zheng. Synthesis and structure-activity relationships of 5-phenyloxazole-2-carboxylic acid derivatives as novel inhibitors of tubulin polymerization. Bioorganic & Medicinal Chemistry Letters, 2021, 3, 127968.
（8） Yan-Yan Ma, Deng-Gao Zhao*, Ruiqiang Zhang, Xuan He, Bao Qiong Li, Xiang-Zhi Zhang, Zijian Wang and Kun Zhang*. Identification of bioactive compounds that contribute to the α-glucosidase inhibitory activity of rosemary. Food & Function, 2020, 11, 1692-1701.
